Ascendis Pharma A/S Announces Closing of Initial Public Offering, Including Full Exercise of Underwriters’ Option to Purchase Additional Shares

Copenhagen, Denmark, February 2, 2015 ‐ Ascendis Pharma A/S (Nasdaq: ASND), a clinical stage biopharmaceutical company, today announced the closing of its initial public offering of 6,900,000 American Depositary Shares (ADSs) at a price to the public of $18.00 per ADS, which includes the exercise in full by the underwriters of their option to purchase additional ADSs. Ascendis estimates net proceeds from the offering to be approximately $111.5 million, after deducting underwriting commissions and estimated offering expenses.

BofA Merrill Lynch and Leerink Partners LLC acted as joint book‐running managers for the offering. Wells Fargo Securities acted as co‐manager.

The offering was made solely by means of a prospectus, copies of which may be obtained by contacting BofA Merrill Lynch, 222 Broadway, New York, NY 10038, Attn: Prospectus Department, or by email at dg.Prospectus_Requests@baml.com; or Leerink Partners LLC, Attention: Syndicate Department, One Federal Street, 37th Floor, Boston, MA 02110, by email at syndicate@leerink.com, or by phone at (800) 808‐7525.

A registration statement relating to these securities was declared effective by the Securities and Exchange Commission on January 27, 2015. Copies of the registration statement, as amended, can be accessed through the SEC's website at www.sec.gov.

This press release shall not constitute an offer to sell or the solicitation of an offer to buy, nor shall there be any sale of these securities in any state or jurisdiction in which such an offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state or jurisdiction.

About Ascendis Pharma A/S
Ascendis Pharma A/S is a clinical stage biopharmaceutical company applying its TransCon technology to develop a pipeline of long‐acting prodrug therapies with best‐in‐class profiles to address large markets with significant unmet medical needs.

Contact:
Investor Contact:
Martin Auster, M.D.
Chief Business Officer
(650) 617‐3403
ir@ascendispharma.com

Media Contact:
Marion Janic
Rooney & Associates
(212) 223‐4017
mjanic@rooneyco.com